Editas Medicine to Present Preclinical Data on Novel Engineered iPSC Derived NK Cells for the Treatment of Cancer at the Society for Immunotherapy of Cancer 36th Annual Meeting
The Company will present a poster on its new method to drive high-level constitutive CD16 expression on the surface of iPSC-derived natural killer (iNK) cells through transgene knock-in (KI) at the GAPDH locus using an Editas-engineered AsCas12a. New preclinical data demonstrated that CD16 KI confers significantly increased cytotoxic activity in iNK cells against tumor cells compared with wild type iNK cells.
Full details of the
Title: GAPDH Knock-in of High Affinity CD16 in iPSC
Date and Time: Friday, November 12, 2021,
Abstract #: 191
Session Title: Cellular Therapies
About Editas Medicine
As a leading genome editing company,
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Source: Editas Medicine, Inc.